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Mysterious things are happening at Roseville Retirement Home to patients taking Bayer’s new hearing loss treatment, Sonifex.

You have 24 hours… can you solve all three mysteries in time?

Sonifex is not a real product and bears no similarity to existing medication in Bayer’s portfolio.

The patient cases are also fictitious and exaggerated, and have been created for educational purposes only. Privacy Statement.

Welcome! I’m Dr. Omar Greenman, the Head Doctor of Roseville Retirement Home.
Call me Dr. Omar!

There are three curious cases to solve at the Roseville Retirement Home...

…all these cases involve patients suffering from hearing loss.

My first choice of medication for people with hearing loss is Sonifex, a new Bayer injection. It has strong supporting clinical trial data, and is popular with both doctors and patients.

But despite this, Sonifex seems to be the common factor amongst all the patients involved.

Walk into my office by clicking on the door, to meet Dr. Louisa Aeventus, Bayer’s patient safety expert.

I need you to work with her, talk to residents and get to the bottom of this before any more people are affected.

Choose your actions wisely to solve the mysteries within 24 hours. The faster you act, the faster we can help protect our patients…

Hi! I’m Dr. Louisa Aeventus, and I work at Bayer as a patient safety expert. I’ll be helping you out on your mission today.

We need to solve three curious cases…

I’ll be keeping track of key findings on my clipboard. The clipboard icon will be available to click on whenever we have relevant notes to review.

At any point in the game you can access my medical briefcase if you need to refer to background information on Sonifex. Just click on the briefcase icon.

You’re all set to solve the Three Curious Cases.

Remember that you only have 24 hours – the decisions you make throughout the game will impact the time it takes you to solve each case – so try to be as fast as you can... GOOD LUCK!

Click on the case you’d like to investigate first:

Click on the case you’d like to investigate next:

Click on the below to find out how you did…

Some of these patients have the hiccups! Select the questions you’d like to ask first:

Some of these patients have the hiccups! Select the question you’d like to ask next:

Tell me a bit more about how you’re feeling
Tell me about your treatment

Hicc. My hearing has improved, hicc, since I started injecting Sonifex twice a week. Hicc!

I’ve been injecting Sonifex and my hearing has improved drastically. I’m lucky I’m so healthy and take no other medicines

I’m so so. I’ve, hicc, been taking Sonifex twice a week. Hicc, it’s easy to remember when to take it as I, hicc, take it at the same time as Jointalin, my arthritis medication.

Click the icon to add this information to your clipboard

I’ve, hicc, set myself a reminder to take, hicc, both Sonifex and my arthritis, hicc, medication, Jointalin, at 12:00 twice a week.

I’ve been taking Sonifex twice a week for two weeks, and I feel great!

I’ve been injecting, hicc, Sonifex into my tummy for, hicc, two weeks now, hicc!

Click the icon to add this information to your clipboard

Do you think you know the cause of the hiccups?

HINT: Check your clipboard to see what seems out of place.
You’ve incurred a 2 hour time penalty

Yes
No

Based on the information you have on your clipboard, what do you think is the cause of the hiccups?

I’m afraid that’s incorrect.

All three patients are taking Sonifex twice a week. You’ve received a 1 hour time penalty.

HINT: Check your clipboard to see what stands out.

I’m afraid that’s incorrect.

All three patients are correctly injecting Sonifex into their tummies. You’ve incurred a 1 hour time penalty.

HINT: check your clipboard to see what stands out.

Ah! That must be right.

Sonifex seems to be affected by the arthritis medication, Jointalin, that Lina and Jonas have been taking.

The frequency of Sonifex doses
The way Sonifex is taken
Other medicines affecting Sonifex

The interaction between the arthritis medication, Jointalin, and Sonifex has caused an adverse event – the hiccups.

What do you think you should do with this information?

Well done for taking this action, however this information also needs to be reported back to Bayer.

Did you know that patients, caregivers and doctors can all report adverse events? It’s also important for Lina and Jonas to see Dr. Omar for him to be aware of this medicine interaction.

You’ve incurred a 2 hour time penalty.

Well done, it is important to report any adverse event.

You should have also encouraged Lina and Jonas to make an appointment with Dr. Omar. It’s important for the doctor to be aware of this medicine interaction.

You’ve incurred a 2 hour time penalty.

Well done, that’s the correct answer!

Not only is it important for Lina and Jonas to speak to Dr. Omar, but it’s also important for them to report the adverse event to Bayer!

Tell Lina and Jonas to make an appointment with Dr. Omar
Work with Lina and Jonas to report this to Bayer as an adverse event
Both of the above

An adverse event is an untoward or unintended medical occurrence in a patient after exposure to a medicine, which is not necessarily caused by that medicine.

CONGRATULATIONS!

You’ve discovered that the hiccups are caused by Jointalin, an arthritis medication affecting Sonifex – this is called a drug-drug interaction.

The information you shared with Bayer is currently being analyzed – before the end of the game you will see how the information has been used to help avoid this adverse event from affecting other patients in the future!

A drug-drug interaction is a change in a drug’s effect on the body when it is taken together with a second drug. This can lead to unwanted side effects.

00.00

Boris has developed a green rash!

Select the question you’d like to ask him:

How are you feeling?
How long have you had this green rash for?

WHAT?

I CAN’T HEAR YOU!

Click here to ask the question louder:
“HOW ARE YOU FEELING, BORIS?”
Click here to ask the question louder:
“HOW LONG HAVE YOU HAD THIS GREEN RASH FOR, BORIS?

Oh, sorry! I’ve been feeling funny since I started taking Sonifex twice a week, two weeks ago. The medicine tastes so sweet, yum yum! But, my hearing hasn’t improved at all and I’ve had this green rash since!

What was odd about Boris’ answers?

Well spotted!

Boris said Sonifex was sweet, but he should be injecting the medication, not drinking it!

That’s incorrect.

Boris said he is taking Sonifex twice a week, as per Dr. Omar’s instructions.

You’ve incurred a 3 hour time penalty. HINT: Have a look at my toolbox to see how Sonifex should be taken.

That’s incorrect.

Boris said he has been taking Sonifex for two weeks.

You’ve incurred a 3 hour time penalty. HINT: Have a look at my toolbox to see how Sonifex should be taken.

Why don’t you have a look at my toolbox to see how Sonifex should be taken.

You’ve incurred a 1 hour time penalty.

How he takes Sonifex
How frequently he takes Sonifex
Length of time he’s taken Sonifex
I’m not sure

What should you do with this information?

Select all that apply:

That’s not entirely correct!

Whilst it’s important to work with Boris to report your findings to Bayer, you should also encourage him to speak to Dr. Omar about how to take Sonifex correctly.

You’ve incurred a 2 hour time penalty.

That’s not entirely correct!

Whilst it’s important to encourage Boris to speak to Dr. Omar about how to take Sonifex correctly, you should also work with him to report your findings to Bayer.

You’ve incurred a 2 hour time penalty.

That’s incorrect!

It’s important to work with Boris to not only report your findings to Bayer, but also encourage him to speak with Dr. Omar about how to take Sonifex correctly.

You’ve incurred a 2 hour time penalty.

Well done! You’re right.

It’s important to not only report your findings to Bayer, but to also encourage Boris to speak to Dr. Omar about how to take Sonifex correctly!

That’s not entirely correct!

Whilst it’s important to encourage Boris to speak to Dr. Omar about how to take Sonifex correctly, it’s not your duty to give him medical advice directly. Instead, you should work with him to report your findings to Bayer.

You’ve incurred a 2 hour time penalty.

That’s not entirely correct!

Whilst it’s important to work with Boris to report your findings to Bayer, it’s not your duty to give him medical advice directly. Instead, you should encourage him to speak to Dr. Omar about how to take Sonifex correctly.

You’ve incurred a 2 hour time penalty.

That’s not entirely correct!

Whilst it’s important to work with Boris to report your findings to Bayer, and to encourage him to speak to Dr. Omar about how to take Sonifex correctly, it’s not your duty to give him medical advice directly.

You’ve incurred a 2 hour time penalty.

Work with Boris to report the adverse event to Bayer
Urge Boris to speak to Dr. Omar
SUBMIT

CONGRATULATIONS!

You’ve discovered that the green rash is caused by taking Sonifex incorrectly. This would be considered an adverse event.

The information you shared with Bayer is currently being analyzed – before the end of the game you will see how the information has been used to help avoid this adverse event from affecting other patients in the future!

An adverse event is an untoward or unintended medical occurrence in a patient after exposure to a medicine, which is not necessarily caused by that medicine.

00.00

I’m Sakiko and this is Felipe, my husband. Sonifex has worked wonders! He can now hear me, and what’s better is that he was bald before he started taking Sonifex, and now, look at him – his hair has grown!

Select the question you’d like to ask Sakiko first:

Select the question you’d like to ask Sakiko next:

No, Felipe hasn’t changed his routine at all. He’s been using the same shampoo for the past 60 years – he’s loyal!

Although… he has started taking an afternoon nap most days. Dr. Omar told us he may experience fatigue as a result of taking Sonifex, and this is definitely true!

Oh, he loves to take it daily, with his porridge in the morning and just after dinner.

Has Felipe changed his daily routine recently?
When does Felipe take Sonifex?

Do you want to ask Sakiko another question?

Yes
No, I think I’ve figured it out. Let’s move on!

What other question do you want to ask Sakiko?

Felipe injects Sonifex into his tummy, just like Dr. Omar told him to! He doesn’t like needles much, but he knows he needs to take it properly.

Felipe’s been taking Sonifex for two weeks now! He can finally hear me when I ask him to fetch me a cup of tea.

How does Felipe take Sonifex?
How long has Felipe been taking Sonifex for?

I’m glad you asked Sakiko all of the questions. It’s important to get as much information as you can. Let’s move on to solving the case!

What is causing Felipe’s hair growth?

HINT: Go look at my toolbox to see how frequently Felipe should be taking Sonifex.

You’ve incurred a 1 hour time penalty!

That’s right!

That’s not right.

You’ve incurred a 2 hour time penalty – go back and ask Sakiko the other questions.

I still don’t know
He’s always sleeping
He’s taking another medicine
He’s not taking Sonifex properly

You’ve figured out that Felipe isn’t taking Sonifex properly.

What do you think he’s doing wrong?

Unfortunately that’s incorrect.

You’ve incurred a 3 hour time penalty.

Felipe is taking Sonifex twice daily not twice per week! That’s what must be causing the hair growth!

Let’s go report this to Bayer.

Ah! That’s right – Felipe is taking Sonifex twice daily not twice per week! That’s what must be causing the hair growth!

Let’s go report this to Bayer.

You’ve incurred a 2 hour time penalty!

Why don’t you check the information in the medicine briefcase and identify what Felipe has done wrong?

He’s taking it orally, not injecting it
He’s taking it too frequently
I’m not sure

Ok, so what should Sakiko mention in the adverse event report?

Select all that apply:

Well done, that’s the correct answer!

Sakiko told you that Felipe is taking Sonifex too frequently and that not only is he tired (a known side effect), but his hair is growing rapidly.

It’s important to report all the information that you have, including both known and unknown side effects.

Unfortunately, that’s not entirely correct.

You’ve incurred a 1 hour time penalty!

It’s important to report both known and unknown side effects, as well as all of the available information you have, so the adverse event can be analyzed appropriately. Try again…

Unfortunately, that’s not right.

You’ve incurred a 2 hour time penalty!

It’s important to report both known and unknown side effects, as well as all of the available information you have, so the adverse event can be analyzed appropriately. Try again…

He’s using the same shampoo
He’s tired
He’s taking it more frequently than he should be
He experienced hair growth
SUBMIT

An adverse event is an untoward or unintended medical occurrence in a patient after exposure to a medicine, which is not necessarily caused by that medicine.

CONGRATULATIONS!

You’ve discovered that Felipe’s hair growth was caused by him taking Sonifex twice a day – this is known as an unexpected therapeutic effect.

The information you shared with Bayer is currently being analyzed – before the end of the game you will see how the information has been used by Bayer to help patients in the future!

An unexpected therapeutic effect is an unexpected or unintended response after treatment of any kind, the results of which are judged to be useful or favorable.

00.00

Thank you so much for your detective work!

You solved the Three Curious Cases and contributed to new materials and medications
for the future!

FINAL SCORE

Time taken: 00.00

Click below to share this game with friends and help spread the message about the importance of reporting adverse events

PLAY AGAIN?

Unfortunately you did not solve the Three Curious Cases in 24 hours as you incurred too many penalties.

Click below to try again!

FINAL SCORE

Time taken: 00.00

Click below to share this game with friends and help spread the message about the importance of reporting adverse events

TRY AGAIN?